Preoperative MRI brain phenotypes are related to postoperative delirium in older individuals

• Six distinct MRI brain phenotypes were found in older patients scheduled for surgery. A combined analysis of markers could reflect delirium predisposition. multi-burden pathology phenotype shows a higher odds developing delirium. assist the understanding predisposition to The underlying structural correlates postoperative remain largely unknown. preoperative magnetic resonance imaging (MRI) improve our pathophysiology Therefore, we aimed identify different major elective surgery, and assess relation between these Markers neurodegenerative neurovascular changes determined from scans (n = 161, mean age 71, standard deviation 5 years), whom 24 (15%) developed hierarchical cluster was performed. We six groups with phenotypes. Logistic regression showed individuals 15 (9%), ratio (95% confidence interval): 3.8 (1.1–13.0)). In conclusion, results indicate that are related risk after an improved